Tukysa 150mg Tablet (Tucatinib)
Prescription RequiredManufactured By
Seagen
Pack Of
60
Salt Composition
Tucatinib
Storage
Keep in cold place
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Tucaxen 150mg Tablet
Overview
Tukysa 150mg Tablet is a prescription-based anticancer medicine used in the treatment of advanced or metastatic HER2-positive breast cancer, & colon and rectum cancer (colorectal cancer). The active ingredient of the Tukysa is Tucatinib which belongs to the drug class of Kinase inhibitors.
It controls the growth & multiplication of cancer cells by inhibiting the function of abnormal protein or enzyme. Tucatinib Tablet is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Tukysa 150mg Tablet (Tucatinib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Tucatinib Tablet are mentioned below:
● Fever
● Fatigue
● Diarrhea
● Headache
● Weight gain
● Eye dryness
● Hemorrhage
● Muscles pain
● Breathlessness
● Abdominal pain
● Nausea & Vomiting
● Swelling in face, legs, and feet
How To Use
Tucatinib 150mg Tablet (Tukysa) is a prescription-based anticancer drug that should be administered orally. Tukysa is taken orally with or without food as per the doctor's advice.
It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the tablet, take it as a whole.
Reference
● Shah, M., Wedam, S., Cheng, J., Fiero, M. H., Xia, H., Li, F., ... & Beaver, J. A. (2021). FDA approval summary: tucatinib for the treatment of patients with advanced or metastatic HER2-positive breast cancer. Clinical Cancer Research, 27(5), 1220-1226.
● Okines, A. F., Curigliano, G., Mizuno, N., Oh, D. Y., Rorive, A., Soliman, H., ... & Pohlmann, P. R. (2025). Tucatinib and trastuzumab in HER2-mutated metastatic breast cancer: a phase 2 basket trial. Nature medicine, 31(3), 909-916.
● Topletz-Erickson, A., Lee, A., Rustia, E. L., Sun, H., Mayor, J. G., Abdulrasool, L. I., ... & Endres, C. J. (2022). Evaluation of Safety and Clinically Relevant Drug–Drug Interactions with Tucatinib in Healthy Volunteer s. Clinical Pharmacokinetics, 61(10), 1417.
● Sirhan, Z., Thyagarajan, A., & Sahu, R. P. (2022). The efficacy of tucatinib-based therapeutic approaches for HER2-positive breast cancer. Military Medical Research, 9(1), 39.
● Murthy, R. K., Loi, S., Okines, A., Paplomata, E., Hamilton, E., Hurvitz, S. A., ... & Winer, E. P. (2020). Tucatinib, trastuzumab, and capecitabine for HER2-positive metastatic breast cancer. New England Journal of Medicine, 382(7), 597-609.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Tukysa 150mg Tablet (Tucatinib). It is advised to consult your doctor for further information.
- • Pregnancy: Tucatinib 150mg Tablet (Tukysa) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Tukysa 150mg Tablet is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Tucatinib 150mg Tablet (Tukysa).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Tukysa 150mg Tablet (Tucatinib).
- • Liver: Inform your doctor before starting Tucatinib 150mg Tablet (Tukysa) if you have liver disease to avoid any serious side effects
FAQs
Why do doctors prescribe Tukysa 150mg Tablet (Tucatinib)?
This medicine is given to patients diagnosed with certain types of breast, colon, and rectum cancer.
What is the right way of taking the Tukysa 150mg Tablet (Tucatinib)?
Tukysa is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the tablet; take it as a whole.
What are the commonly observed side effects of Tucatinib 150mg Tablet (Tukysa)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine the liver function.
Who should avoid taking the Tukysa 150mg Tablet (Tucatinib)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Tucatinib 150mg Tablet (Tukysa) be given in combination therapy with other medications?
Yes, Tucatinib 150mg Tablet can be given in combination therapy with other medications to treat different kind of cancers and to increase the effectiveness of the treatment.
Marketer Details
Seagen
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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