Keytruda 100mg Injection (Pembrolizumab)
Prescription RequiredManufactured By
Msd pharmaceuticals pvt ltd
Pack Of
1
Salt Composition
Pembrolizumab
Storage
Keep in cold place
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Overview
Keytruda 100mg injection is a prescription-based anticancer medicine used in the treatment of advanced melanoma (a type of skin cancer), non-small cell lung cancer, Hodgkin & large B-cell lymphoma, bladder cancer, gastric cancer, head & neck cancer, and cervical cancer. The active ingredient of Keytruda is pembrolizumab, which belongs to the drug class of PD-1 (Programmed Cell Death Protein 1) inhibitors. As a checkpoint inhibitor, pembrolizumab inhibits the PD-1 protein on immune T-cells, enabling your immune system to detect and destroy cancer cells. The injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
The injection is administered as an intravenous infusion by a qualified doctor in a hospital or clinical setting. The doctor determines the dosage of the Pembrolizumab 100mg injection according to the type of cancer, treatment regimen, age, and overall health of the patient. It should not be self-administered. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects can include tiredness, weakness, rash, itching, diarrhea, nausea, decreased appetite, constipation, cough, and shortness of breath. Most of the pembrolizumab 100mg injection side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.
Patients must list all medicines, supplements, and herbal products that they are taking. Also, inform your doctor about autoimmune disorders, organ transplantation, and previous immune-related reactions before the treatment. The pembrolizumab 100mg injection must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Head and neck cancer, lung cancer, skin cancer, gastric cancer
Side Effects
The human body shows undesired symptoms after taking Keytruda 100mg injection (pembrolizumab). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Keytruda injection are mentioned below:
- ● Fever
- ● Fatigue
- ● Dry skin
- ● Diarrhea
- ● Headache
- ● Weight loss
- ● Constipation
- ● Breathlessness
- ● Loss of appetite
- ● Nausea and vomiting
- ● Muscles and join pain
Serious Side Effects
- ● Diabetes
- ● Hepatitis
- ● Lung infection
- ● Colon infection
- ● Skin inflammation
- ● Decrease in level of white blood cells
How To Use
Pembrolizumab 100mg injection (Keytruda) is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Reference
● Khoja, L., Butler, M. O., Kang, S. P., Ebbinghaus, S., & Joshua, A. M. (2015). Pembrolizumab. Journal for immunotherapy of cancer, 3(1), 36.
● Bryant, A. K., Lewy, J. R., Bressler, R. D., Chopra, Z., Gyori, D. J., Bazzell, B. G., ... & Strohbehn, G. W. (2024). Projected environmental and public health benefits of extended-interval dosing: an analysis of pembrolizumab use in a US national health system. The Lancet Oncology, 25(6), 802-810.
● Garon, E. B., Rizvi, N. A., Hui, R., Leighl, N., Balmanoukian, A. S., Eder, J. P., ... & Gandhi, L. (2015). Pembrolizumab for the treatment of non–small-cell lung cancer. New England journal of medicine, 372(21), 2018-2028.
● Bellmunt, J., De Wit, R., Vaughn, D. J., Fradet, Y., Lee, J. L., Fong, L., ... & Bajorin, D. F. (2017). Pembrolizumab as second-line therapy for advanced urothelial carcinoma. New England Journal of Medicine, 376(11), 1015-1026.
● Deeks, E. D. (2016). Pembrolizumab: a review in advanced melanoma. Drugs, 76(3), 375-386.
● Silva, V., & Matos, C. (2024). Recent updates in the therapeutic uses of Pembrolizumab: a brief narrative review. Clinical and Translational Oncology, 26(10), 2431-2443.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Keytruda 100mg injection (pembrolizumab). It is advised to consult your doctor for further information.
- • Pregnancy: Pembrolizumab 100mg injection may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Keytruda 100mg injection (pembrolizumab) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Pembrolizumab 100mg injection (Keytruda).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Keytruda 100mg injection (pembrolizumab).
- • Liver: Inform your doctor before starting Keytruda 100mg injection (pembrolizumab) if you have liver disease to avoid any serious side effects.
FAQs
Is keytruda 100mg injection a chemotherapy drug?
No, Keytruda injection is neither a chemotherapy nor a radiation therapy drug. It is an immunotherapy drug that boosts immunity to kill cancer cells.
How do I know if Keytruda is working?
Your doctor will go for a test to monitor your tumor size. A scan or image test will show a detailed image. Reduction in tumor size will be considered a positive effect of the injection.
How does Pembrolizumab 100mg injection (Keytruda) kill the cancer cells?
It blocks the action of a protein that activates the immune system. Consequently, our system starts to identify cancer cells and kill them. Furthermore, through this process, it slows down the growth and spreading of the cancer cells to nearby organs.
How much time does Keytruda take to show results?
The time depends on the stage of cancer diagnosed and how the patient's body is responding. It may take days to weeks to show results. It is advised to consult your doctor to know the details.
Is Pembrolizumab 100mg injection a combination drug?
Yes, Pembrolizumab 100mg injection can be combined with other cancer treatments such as chemotherapy, radiation therapy, and targeted therapy to provide better outcomes and make treatment more effective.
Is it possible for the patients to continue doing their normal daily routine?
Yes, it is normal for many patients to continue performing daily activities while taking Keytruda 100mg Injection. However, some may experience adverse effects that decrease their ability to function.
Marketer Details
Msd pharmaceuticals pvt ltd
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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