Perfecine 200mg Tablet (Pirfenidone)
Prescription RequiredManufactured By
Arechar Healthcare
Pack Of
100
Salt Composition
Pirfenidone
Storage
Keep in cold place
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Pirfenex 200mg Tablet
Overview
Perfecine 200mg Tablet is a prescription-based medicine used in the treatment of idiopathic pulmonary fibrosis, a chronic lung disease that causes progressive scarring and stiffness of lung tissue. The active ingredient of Perfecine is pirfenidone, which belongs to the drug class of transforming growth factor inhibitors. It helps reduce the formation and progression of fibrotic tissue in the lungs, which may help decrease the decline in lung function. The medicine is not intended to reverse the existing lung fibrosis or to cure the disease completely.
The tablet must be taken orally and swallowed whole with water and should not be crushed, chewed, or opened. The prescribed dose and duration of the pirfenidone 200mg tablet depend on the patient's condition and response to treatment. It is taken with food to reduce stomach-related problems. Doctors usually start the treatment at a lower dose and gradually increase according to the patient's response. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects can include nausea, indigestion, diarrhea, vomiting, loss of appetite, tiredness, headache, dizziness, stomach discomfort, and skin reactions or increased sensitivity to sunlight. Most of the Pirfenidone 200mg tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.
Patients should avoid excessive exposure to sunlight and use protective clothing and sunscreen because the medicine can increase sun sensitivity. Pregnant or breastfeeding women should consult their doctor before using the Pirfenidone 200mg tablet. Patients must list all medicines, supplements, and herbal products that they are taking. The tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Idiopathic pulmonary fibrosis
Side Effects
The human body shows undesired symptoms after taking Perfecine 200mg Tablet (Pirfenidone). Usually, they disappear with time as the body adjusts to the medicine. These side effects do not need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Perfecine Tablet are mentioned below:
- ● Cough
- ● Dizziness
- ● Diarrhea
- ● Headache
- ● Tiredness
- ● Indigestion
- ● Weight loss
- ● Constipation
- ● Breathlessness
- ● Sinus infection
- ● Loss of appetite
- ● Changes in taste
- ● Sensitivity to light
- ● Nausea & Vomiting
- ● Difficulty sleeping
Serious Side Effects
- ● Liver inflammation
- ● Severe allergic reactions
- ● Upper respiratory tract infection
How To Use
Take Pirfenidone 200mg Tablet (Perfecine) in dosage as prescribed by the doctor. Dosage and the duration determined as per patients health condition. This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken with food. Never skip a dose or double dose.
Reference
● Behr, J., Prasse, A., Kreuter, M., Johow, J., Rabe, K. F., Bonella, F., ... & Froehling, K. P. (2021). Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial. The Lancet Respiratory Medicine, 9(5), 476-486.
● Noble, P. W., Albera, C., Bradford, W. Z., Costabel, U., Glassberg, M. K., Kardatzke, D., ... & Du Bois, R. M. (2011). Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. The Lancet, 377(9779), 1760-1769.
● Lopez-de la Mora, D. A., Sanchez-Roque, C., Montoya-Buelna, M., Sanchez-Enriquez, S., Lucano-Landeros, S., Macias-Barragan, J., & Armendariz-Borunda, J. (2015). Role and new insights of pirfenidone in fibrotic diseases. International journal of medical sciences, 12(11), 840.
● Aimo, A., Spitaleri, G., Panichella, G., Lupón, J., Emdin, M., & Bayes-Genis, A. (2022). Pirfenidone as a novel cardiac protective treatment. Heart failure reviews, 27(2), 525-532.
● Richeldi, L., Yasothan, U., & Kirkpatrick, P. (2011). Pirfenidone. Nature Reviews Drug Discovery, 10(7), 489-490.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Perfecine 200mg Tablet (Pirfenidone). It is advised to consult your doctor for further information.
- ● Pregnancy: Pirfenidone 200mg Tablet (Perfecine) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Perfecine 200mg Tablet (Pirfenidone) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Pirfenidone 200mg Tablet (Perfecine).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Perfecine 200mg Tablet (Pirfenidone).
- ● Liver: Inform your doctor before starting Pirfenidone 200mg Tablet (Perfecine) if you have liver disease to avoid any serious side effects.
FAQs
What disease is treated using Perfecine 200mg Tablet (Pirfenidone)?
Perfecine Tablet is an prescription based medicine used to treat idiopathic pulmonary fibrosis.
Is it safe to give Pirfenidone 200mg Tablet (Perfecine) to children?
No, it is considered safe for children. It is advised to take consultation with your doctor before taking it.
What is the correct way to take Perfecine 200mg Tablet (Pirfenidone)?
This medicine is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the capsules; take them as a whole.
What are the commonly observed side effects of Pirfenidone 200mg Tablet (Perfecine)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine the liver function.
What should be done if miss a dose of Perfecine 200mg Tablet (Pirfenidone)?
It is advised not to miss any scheduled dosage of Perfecine. In case you miss a dose, consult your doctor immediately. Don't overdose to compensate for the missed one.
Marketer Details
Arechar Healthcare
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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