Opdivo 100mg Injection (Nivolumab)
Prescription RequiredManufactured By
Bristol-myers squibb pharma
Pack Of
1
Salt Composition
Nivolumab
Storage
Keep in cold place
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Opdivo 40mg Injection
Overview
Opdivo 100mg Injection is a prescription-based anticancer medicine used in the treatment of non-small cell lung cancer, kidney cancer, head and neck cancer, melanoma, Hodgkin's disease, and liver cancer.
The active ingredient of the Opdivo is Nivolumab which belongs to the drug class of PD-1 (Programmed Cell Death Protein 1) Inhibitors. As a checkpoint inhibitor, Nivolumab inhibits the PD-1 protein on immune T-cells, enabling your immune system to detect and destroy cancer cells.
Nivolumab Injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Nivolumab 100mg Injection (Opdivo). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Opdivo Injection are mentioned below:
- ● Rash
- ● Fever
- ● Fatigue
- ● Diarrhea
- ● Dizziness
- ● Headache
- ● Weakness
- ● Weight gain
- ● Constipation
- ● Muscles pain
- ● Appetite loss
- ● Low RBC count
- ● Change in taste
- ● Abdominal pain
- ● Swelling in body
- ● Sensitivity to light
- ● Low blood pressure
- ● Mouth inflammation
- ● Nausea and vomiting
- ● Respiratory tract infection
Serious Side Effects
- ● Seizures
- ● Confusion
- ● Eye disorder
- ● Hormonal imbalance
- ● Infection in liver and colon
How To Use
Opdivo 100mg Injection (Nivolumab) is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Reference
● Larkin, J., Chiarion-Sileni, V., Gonzalez, R., Grob, J. J., Rutkowski, P., Lao, C. D., ... & Wolchok, J. D. (2019). Five-year survival with combined nivolumab and ipilimumab in advanced melanoma. New England journal of medicine, 381(16), 1535-1546.
● Carbone, D. P., Reck, M., Paz-Ares, L., Creelan, B., Horn, L., Steins, M., ... & Socinski, M. A. (2017). First-line nivolumab in stage IV or recurrent non–small-cell lung cancer. New England Journal of Medicine, 376(25), 2415-2426.
● Ferris, R. L., Blumenschein Jr, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., ... & Gillison, M. L. (2016). Nivolumab for recurrent squamous-cell carcinoma of the head and neck. New England Journal of Medicine, 375(19), 1856-1867.
● Deeks, E. D. (2014). Nivolumab: a review of its use in patients with malignant melanoma. Drugs, 74(11), 1233-1239.
● Gunturi, A., & McDermott, D. F. (2015). Nivolumab for the treatment of cancer. Expert opinion on investigational drugs, 24(2), 253-260
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Nivolumab 100mg Injection (Opdivo). It is advised to consult your doctor for further information.
- • Pregnancy: Opdivo 100mg Injection (Nivolumab) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Nivolumab 100mg Injection (Opdivo) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Opdivo 100mg Injection (Nivolumab).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Opdivo 100mg Injection (Nivolumab).
- • Liver: Inform your doctor before starting Opdivo 100mg Injection (Nivolumab) if you have liver disease to avoid any serious side effects
FAQs
What cancers are treatable with Nivolumab 100mg Injection (Opdivo)?
This injection is used to treat non-small cell lung cancer, kidney cancer, head and neck cancer, melanoma, Hodgkin's disease, and liver cancer.
Does Opdivo 100mg Injection have any effect on fertility?
There is limited research present on the effect of injection on fertility. However, consult your doctor in prior if you are planning to be pregnant in future.
Which type of drug is Nivolumab 100mg Injection (Opdivo)?
Nivolumab 100mg Injection is a kind of immunotherapy drug that stimulates the immune system to kill cancer cells.
Is it safe to use Opdivo in children?
No, the use of Opdivo injection is restricted in children below 18 years.
Is it safe to give Opdivo 100mg Injection (Nivolumab) to diabetic patients?
No, taking Opdivo may elevate blood sugar levels. So consult with your doctor before taking it.
Marketer Details
Bristol-myers squibb pharma
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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