Ibruxen 140mg Capsule (Ibrutinib)
Prescription RequiredManufactured By
Everest
Pack Of
120
Salt Composition
Ibrutinib
Storage
Keep in cold place
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Overview
Ibruxen 140mg Capsule is a prescription-based targeted anticancer medicine used in the treatment of blood cancer such as mantle cell lymphoma (MCL), chronic lymphocytic leukaemia (CLL), small lymphocytic lymphoma (SLL), Waldenstrom’s macroglobulinemia, and marginal zone lymphoma (MZL). The active ingredient of Ibruxen is Ibrutinib, which belongs to the drug class of Bruton’s tyrosine kinase (BTK) inhibitors. It works by blocking the action of abnormal BTK protein to control the growth of cancer cells. By inhibiting this pathway, it helps slow the growth and spread of cancerous B cells. Ibrutinib 140mg capsule is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
The capsule must be taken orally and swallowed whole with water and should not be crushed, chewed, or opened. The prescribed dose and duration of the Ibrutinib 140mg capsule depend on the patient's condition and response to treatment. It can also be taken with or without food. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects include diarrhea, nausea, tiredness, muscle or joint pain, rash, mouth sores, and bruising. A few patients can undergo severe side effects, including significant bleeding, severe infections, heart rhythm problems, high blood pressure, and liver problems. Most of the Ibrutinib 140mg capsule side effects can leave when the body adapts to the medicine. However, if any side effects persist, inform your doctor immediately.
The medicine may cause fetal harm, so it should not be used during pregnancy. Patients must list all medicines, supplements, and herbal products that they are taking. The Ibrutinib 140mg capsule must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Ibruxen 140mg Capsule. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention.
It is advised to consult your doctor if these symptoms become unmanageable. Some of the common side effects of Ibruxen Capsule (Ibrutinib) are mentioned below:
● High risk of infection
● Vomiting
● Weakness
● Nausea
● Fatigue
● Fever
● Decreased blood cells (red cells, white cells, and platelets)
● Diarrhea
● Cough
How To Use
Ibruxen Capsule (Ibrutinib) is a prescription-based anticancer drug that should be administered orally. It is advised to take this capsule after consulting your healthcare expert. This capsule should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.
Missed Doses
Instructions if you miss a dose
Reference
● Ganatra, S., Sharma, A., Shah, S., Chaudhry, G. M., Martin, D. T., Neilan, T. G., ... & Nohria, A. (2018). Ibrutinib-associated atrial fibrillation. JACC: Clinical Electrophysiology, 4(12), 1491-1500.
● Parmar, S., Patel, K., & Pinilla-Ibarz, J. (2014). Ibrutinib (imbruvica): a novel targeted therapy for chronic lymphocytic leukemia. Pharmacy and Therapeutics, 39(7), 483.
● Deeks, E. D. (2017). Ibrutinib: a review in chronic lymphocytic leukaemia. Drugs, 77(2), 225-236.
● Woyach, J. A., Furman, R. R., Liu, T. M., Ozer, H. G., Zapatka, M., Ruppert, A. S., ... & Byrd, J. C. (2014). Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. New England Journal of Medicine, 370(24), 2286-2294.
● Cameron, F., & Sanford, M. (2014). Ibrutinib: first global approval. Drugs, 74(2), 263-271.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Ibruxen 140mg Capsule (Ibrutinib). It is advised to consult your doctor for further information.
- ● Pregnancy: Ibruxen 140mg Capsule (Ibrutinib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Ibruxen 140mg Capsules (Ibrutinib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Ibruxen 140mg (Ibrutinib).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Ibruxen 140mg Capsule (Ibrutinib).
- ● Liver: Inform your doctor before starting Ibruxen 140mg Capsule (Ibrutinib) if you have liver disease to avoid any serious side effects.
FAQs
Can Ibruxen 140mg Capsule be given to children?
No, children below 18 years of age are not advised to take this medicine as it results in severe complications.
Can Ibruxen Capsule (Ibrutinib) be given to kidney patients?
No, it is advised to avoid taking this medicine if you have serious kidney problems. Consult the doctor before taking this medication.
Is it safe to take Ibruxen 140mg Capsule (Ibrutinib) while driving?
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Ibruxen Capsule.
Can Ibruxen 140mg Capsule (Ibrutinib) be taken in a low blood count?
No, it is recommended to avoid taking this injection if the person has anemia or any blood-related disorder.
Can Ibruxen 140mg Capsule (Ibrutinib) be used during pregnancy?
It is not safe to use this medicine during pregnancy as it causes harmful effects in the developing baby.
Marketer Details
Everest
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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